Oral Sphere

Introduction: SARS-CoV-2 is a single-stranded RNA-enveloped virus. It was the principal causative agent for the global pandemic of COVID-19. Amongst the plethora of systemic and orofacial manifestations from COVID-19 disease and anti-SARS-CoV 2 vaccines, the neurological presentations in the orofacial region have been peculiar. This systematic review aims to document these presentations and understand their association with the viral agent and its vaccines.

Methodology: The research was carried out by electronic searching of database records from December 2019 till December 2023.

Results: This review observed neurological manifestations in the oro- facial region due to COVID-19 disease and anti-SARS-CoV 2 vaccines. The most commonly observed manifestations were trigeminal neuralgia from the COVID disease and Bell’s palsy from the COVID vaccines. The reported number of cases came out to be 6% for bell’s palsy, 90% for trigeminal neuralgia, 1.50% glossopharyngeal neuralgia and 0.01% cases of headaches secondary to neuralgias.

Conclusion: Neurological symptoms are usually associated patients with COVID-19. Trigeminal neuralgia was the most commonly observed neurological symptom in this disease. A deeper insight would enhance oral physicians’ preparedness to improve the screening for accurate diagnosis, appropriate management and concise reporting to the Ministry of Health and Family welfare.

Keywords: COVID-19 disease, orofacial manifestations, neurological manifestations, vaccines, SARS CoV-2